Co-Author of the Karolinska 1000 Consecutive MANTA® Vascular Closure Device Study to Present ...
Teleflex Incorporated (NYSE: TFX), a leading global provider of medical technologies, today announced that Dr. Magnus Settergren*, Asssociate Professor at the Karolinska Institutet, Interventional Cardiologist at Karolinska University Hospital, and Co-Author of the Percutaneous plug-based vascular closure device in 1000 consecutive transfemoral transcatheter aortic valve implantations Study, is scheduled to present at a Teleflex-sponsored Training Pavilion at the Transcatheter Cardiovascular Therapeutics (TCT) conference this Sunday, September 18, 2022 at 10:00 a.m. (ET). TCT is the Cardiovascular Research Foundation's (CRF) annual scientific symposium and the world's foremost educational forum specializing in interventional cardiovascular medicine
WAYNE, Pa., Sept. 15, 2022 (GLOBE NEWSWIRE) -- Teleflex Incorporated (NYSE: TFX), a leading global provider of medical technologies, today announced that Dr. Magnus Settergren*, Asssociate Professor at the Karolinska Institutet, Interventional Cardiologist at Karolinska University Hospital, and Co-Author of the Percutaneous plug-based vascular closure device in 1000 consecutive transfemoral transcatheter aortic valve implantations Study, is scheduled to present at a Teleflex-sponsored Training Pavilion at the Transcatheter Cardiovascular Therapeutics (TCT) conference this Sunday, September 18, 2022 at 10:00 a.m. (ET). TCT is the Cardiovascular Research Foundation's (CRF) annual scientific symposium and the world's foremost educational forum specializing in interventional cardiovascular medicine.
The Karolinska 1000 Consecutive MANTA® Device Study—the largest ever real-world evaluation of the MANTA® Device—demonstrated safety and effectiveness with low complication rates and a short learning curve.1 Results of this study were published in The International Journal of Cardiology.
This single-center, observational study reviewed 1048 consecutive, unselected subjects undergoing transfemoral Transcatheter Aortic Valve Implantation (TAVI) from May 2017 to September 2020 at the Karolinska University Hospital in Stockholm, Sweden. The 18 French MANTA® Device was used by five operators to close the femoral artery access site in 1000 subjects (48 excluded), with the primary outcome being the measure of vascular closure device (VCD)-related major complications according to Valve Academic Research Consortium (VARC)-2 definition criteria.1
The study, which was not sponsored by Teleflex, demonstrated that MANTA® Device related major vascular complications occurred in 4.2% of patients with no significant differences in preoperative characteristics between patients with and without MANTA® Device related major vascular complication.1 This outcome is consistent with the results of the SAFE MANTA IDE Clinical Trial, published in 2019 in Circulation: Cardiovascular Interventions, which demonstrated a 4.2% VARC-2 Major Vascular Complication Rate, as well as The MARVEL Prospective Registry, published in 2020 in Catheterization & Cardiovascular Interventions, which demonstrated a 4.0% VARC-2 Major Vascular Complication Rate.2,3
