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Aldose Reductase Inhibition by AT-001 Alleviates Fibrosis and Adverse Remodeling in Diabetic Cardiomyopathy by Reducing Myocardial Fatty Acid Oxidation

Applied Therapeutics Announces Multiple Data Presentations at the American Heart Association ...

Applied Therapeutics, Inc. (Nasdaq: APLT), a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need, today announced multiple data presentations at the upcoming American Heart Association Scientific Sessions, to be held November 5-7, 2022 in Chicago, IL

By Applied Therapeutics
Published - Oct 31, 2022, 07:04 AM ET
Last Updated - Apr 17, 2024, 02:45 PM EDT
  • Additional preclinical data supports AT-001 as an effective treatment for Diabetic Cardiomyopathy, reducing cardiac fibrosis and adverse remodeling
  • Baseline analysis of Phase 3 ARISE-HF study supports the primary endpoint (cardiac functional capacity as measured by Peak VO2) as an important metric of quality of life and physical functioning in Diabetic Cardiomyopathy patients
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