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Harpoon Therapeutics is a clinical-stage immunotherapy company developing a novel class of T cell engagers that harness the power of the body’s immune system to treat patients suffering from cancer and other diseases.

Harpoon Therapeutics to Present Interim Results from Phase 1 Clinical Trial of T Cell Engager ...

Harpoon Therapeutics, Inc. (Nasdaq: HARP), a clinical-stage immunotherapy company developing novel T cell engagers, today announced that it will present updated interim data from its Phase 1 clinical trial evaluating single-agent HPN217 in relapsed/refractory multiple myeloma (RRMM) in a poster presentation at the 64th American Society of Hematology (ASH) Annual Meeting and Exposition being held in person in New Orleans, Louisiana and virtually from December 10-13, 2022. HPN217 targets B-cell maturation antigen (BCMA) and is based on Harpoon’s proprietary Tri-specific T cell Activating Construct (TriTAC®) platform designed to recruit a patient’s own immune cells to kill tumor cells

By Harpoon Therapeutics
Published - Nov 03, 2022, 09:14 AM ET
Last Updated - Mar 20, 2024, 09:10 AM EDT

SOUTH SAN FRANCISCO, Calif., Nov. 03, 2022 (GLOBE NEWSWIRE) -- Harpoon Therapeutics, Inc. (Nasdaq: HARP), a clinical-stage immunotherapy company developing novel T cell engagers, today announced that it will present updated interim data from its Phase 1 clinical trial evaluating single-agent HPN217 in relapsed/refractory multiple myeloma (RRMM) in a poster presentation at the 64th American Society of Hematology (ASH) Annual Meeting and Exposition being held in person in New Orleans, Louisiana and virtually from December 10-13, 2022. HPN217 targets B-cell maturation antigen (BCMA) and is based on Harpoon’s proprietary Tri-specific T cell Activating Construct (TriTAC®) platform designed to recruit a patient’s own immune cells to kill tumor cells.

“The updated interim results from the Phase 1 trial establish clinical proof of concept of HPN217 in heavily pretreated relapsed/refractory multiple myeloma and provide further clinical validation of our proprietary TriTAC T cell engager platform,” said Julie Eastland, President and Chief Executive Officer of Harpoon Therapeutics. “At ASH 2022, we look forward to presenting updated clinical results from the ongoing HPN217 trial in patients with RRMM, including additional safety, efficacy and pharmacodynamic data from patients enrolled at higher dose levels.”

Details of the ASH poster presentation are as follows:

Abstract Title: Updated Interim Results from a Phase 1 Study of HPN217, a Half-Life Extended Tri-Specific T Cell Activating Construct (TriTAC®) Targeting B Cell Maturation Antigen (BCMA) for Relapsed/Refractory Multiple Myeloma (RRMM)
Publication Number: 3240
Session Number/Title: Session 653 - Myeloma and Plasma Cell Dyscrasias: Prospective Therapeutic Trials: Poster II
Session Date, Time: Sunday, December 11 from 6:00 – 8:00 p.m. CT
Location: Ernest N. Morial Convention Center, Hall D

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