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Weight Loss Drugs-Intermittent
Donna Cooper pets her cat Cade at her home in Front Royal, Va., on Friday, March 1, 2024. Cooper has heard that people gain back weight when they stop using drugs like Wegovy, but she hopes to be an exception. She's on her last box of Wegovy injections. Once she's done, Cooper said she’ll just continue with a strict diet and exercise plan. (AP Photo/Amanda Andrade-Rhoades)

Weight-loss drugs like Wegovy are meant for long-term use. Some patients want to stop

Millions of Americans who have used new obesity drugs like Wegovy to lose weight and improve health are wondering what happens if they stop taking them

By JONEL ALECCIA
Published - Mar 07, 2024, 01:03 AM ET
Last Updated - Mar 07, 2024, 01:03 AM EST

Millions of Americans who have dropped pounds and boosted their health using popular obesity drugs like Wegovy are facing a new dilemma: What happens if they stop taking them?

Many worry, rightly, that they’ll regain weight and revert to old habits. In clinical trials, patients who paused the drugs put back on most of the weight they lost.

But others are gambling on a do-it-yourself strategy to ease off the drugs and stay slim by stretching out doses, taking the medication intermittently or stopping and starting again only if needed.

“To me, it’s a help, it’s an aid,” said Donna Cooper, 62, of Front Royal, Virginia, who lost nearly 40 pounds in nine months using Wegovy along with diet and exercise. “At some point you have to come off of them. I don’t want to be on them forever.”

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